Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD00578 ...
Drug Name Carbenicillin
Molecular Weight 378.4
Molecular Formula C17H18N2O6S
CAS Number 4697-36-3
SMILES [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)C(C(O)=O)C1=CC=CC=C1)C(O)=O
External Links
DRUGBANK DB00578
PubChem Compound 20824
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 1.13 - 1.13 - HANSCH,C ET AL. (1995)
Water Solubility 451.0 mg/L 451 mg/L DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Bioavailability 35.0 % 30-40 % PO, oral; DRUGBANK
Clearance 0.11 L/h/kg 1.9 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 0.17 L/kg 0.17 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 1.0 h 1 h DRUGBANK
Half-life 1.1 h 1.1 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Toxicity LD50 3600.0 mg/kg 3600.0 mg/kg PO, oral; mouse; DRUGBANK
Toxicity LD50 2000.0 mg/kg 2000.0 mg/kg PO, oral; Rattus, Rat; DRUGBANK
Toxicity LD50 500.0 mg/kg 500.0 mg/kg PO, oral; dog; DRUGBANK
Protein Binding 45.0 % 30-60 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1