Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.36 | - | 3.36 | - | SANGSTER (1993) |
| Melting Point | 110.0 | ℃ | 108-112 | ℃ | DRUGBANK |
| Water Solubility | 412.0 | mg/L | 412 | mg/L | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Factor | Reference |
|---|---|---|---|---|---|---|---|
| AUC | 1390.0 | ng.h/ml | 1390.0 | ng.h/ml | PO, oral; Children; | DRUGBANK | |
| Bioavailability | 71.0 | % | 68-74 | % | DRUGBANK | ||
| C Max | 68.0 | ng/ml | 68.0 | ng/ml | PO, oral; Children; | DRUGBANK | |
| Tss | 4.5 | h | 4-5 | h | DRUGBANK | ||
| Clearance | 24.8 | L/h | 24.8 | L/h | Average clearance; normal,healthy; | DRUGBANK | |
| Volume of Distribution | 11.9 | L/kg | 11.9 | L/kg | Apparent volume of distribution; normal,healthy; | DRUGBANK | |
| Half-life | 20.0 | h | 20 | h | elimination half-life; normal,healthy; rheumatoid arthritis; | DRUGBANK | |
| Eliminate Route | 90.0 | % | >90 | % | Urinary excretion; | DRUGBANK | Eliminate Route | 5.0 | % | <5 | % | Faeces excretion; | DRUGBANK | Eliminate Route | 25.0 | % | <25 | % | Unchanged drug; | DRUGBANK |
| Protein Binding | 50.0 | % | 50 | % | plasma proteins; | Plasma Concentration → ; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1