Basic Information
| Drug ID | DDPD00561 |
|
| Drug Name | Doxapram | |
| Molecular Weight | 378.5072 | |
| Molecular Formula | C24H30N2O2 | |
| CAS Number | 309-29-5 | |
| SMILES | CCN1CC(CCN2CCOCC2)C(C1=O)(C1=CC=CC=C1)C1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB00561 | |
| PubChem Compound | 3156 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.6 | - | 3.6 | - | DRUGBANK |
| Melting Point | 218.0 | ℃ | 217-219 | ℃ | Lunsford, C.D. and Cale, A.D. Jr.; U S . Patent 3,192,230; June 29, 1965; assigned to A.H. Robins Company, Inc. |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.32 | L/h/kg | 5.3 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 1.2 | L/kg | 1.2 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 4.1 | h | 4.1 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Toxicity LD50 | 75.0 | mg/kg | ~75 | mg/kg | intravenous injection, IV; mouse; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 60.0 | mg/kg | 40-80 | mg/kg | intravenous injection, IV; dog; cat; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1