Basic Information
| Drug ID | DDPD00556 |
|
| Drug Name | Perflutren | |
| Molecular Weight | 188.0193 | |
| Molecular Formula | C3F8 | |
| CAS Number | 76-19-7 | |
| SMILES | FC(F)(F)C(F)(F)C(F)(F)F | |
| External Links | ||
| DRUGBANK | DB00556 | |
| PubChem Compound | 6432 | |
| PDR | 2871 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.0 | - | 3.0 | - | DRUGBANK |
| Boiling Point | -36.6 | ℃ | -36.6 | ℃ | PhysProp |
| Melting Point | -147.6 | ℃ | -147.6 | ℃ | PhysProp |
| Water Solubility | 5.7 | mg/L | 5.7 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Metabolic | 0 | % | 0 | % | DRUGBANK | |
| Clearance | 35.4 | L/h/kg | 590.71 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 1.6 | L/kg | 1.6 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 0.0317 | h | 1.9 | min | DRUGBANK | |
| Half-life | 0.0200 | h | 0.02 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 10.0 | microL/kg | 10 | microL/kg | intravenous injection, IV | Definity | perflutren lipid microsphere | PDR |
| Max dose for adults | 1.3 | ml | 1.3 | ml | intravenous infusion, iv in drop | Definity | perflutren lipid microsphere | PDR |
| Max dose for geriatric | 10.0 | microL/kg | 10 | microL/kg | intravenous injection, IV | Definity | perflutren lipid microsphere | PDR |
| Max dose for geriatric | 1.3 | ml | 1.3 | ml | intravenous infusion, iv in drop | Definity | perflutren lipid microsphere | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1