Basic Information
| Drug ID | DDPD00536 |
|
| Drug Name | Guanidine | |
| Molecular Weight | 59.0705 | |
| Molecular Formula | CH5N3 | |
| CAS Number | 113-00-8 | |
| SMILES | NC(N)=N | |
| External Links | ||
| DRUGBANK | DB00536 | |
| T3DB | T3D4172 | |
| PubChem Compound | 3520 | |
| PDR | 1920 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -0.6 | - | -0.6 | - | DRUGBANK |
| Melting Point | 50.0 | ℃ | 50 | ℃ | PhysProp |
| Water Solubility | 1840.0 | mg/L | 1840 | mg/L | GREENWALD,I 1926) |
| pKa | 12.5 | - | 12.5 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Metabolic | 0 | % | 0 | % | DRUGBANK | |
| Half-life | 7.5 | h | 7-8 | h | DRUGBANK | |
| Toxicity LD50 | 475.0 | mg/kg | 475.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 475.0 | mg/kg | 475.0 | mg/kg | PO, oral; Rattus, Rat; | T3DB |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 35.0 | mg/kg/day | 35 | mg/kg/day | PO, oral | Guanidine Hydrochloride | guanidine hydrochloride | PDR |
| Max dose for geriatric | 35.0 | mg/kg/day | 35 | mg/kg/day | PO, oral | Guanidine Hydrochloride | guanidine hydrochloride | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1