Basic Information
| Drug ID | DDPD00507 |
|
| Drug Name | Nitazoxanide | |
| Molecular Weight | 307.282 | |
| Molecular Formula | C12H9N3O5S | |
| CAS Number | 55981-09-4 | |
| SMILES | CC(=O)OC1=CC=CC=C1C(=O)NC1=NC=C(S1)[N+]([O-])=O | |
| External Links | ||
| DRUGBANK | DB00507 | |
| PubChem Compound | 41684 | |
| PDR | 1235 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 1.63 | - | 1.63 | - | DRUGBANK |
| Boiling Point | 394.0 | ℃ | 394 | ℃ | DRUGBANK |
| Melting Point | 202.0 | ℃ | 202 | ℃ | DRUGBANK |
| Water Solubility | 0.000189 | - | 0.000189 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 7.3 | h | 7.3 | h | DRUGBANK | |
| Toxicity LD50 | 10000.0 | mg/kg | >10000 | mg/kg | PO, oral; dog; rodents; | DRUGBANK |
| Eliminate Route | 66.7 | % | ~66.7 | % | Faeces excretion; PO, oral; | DRUGBANK | Eliminate Route | 33.3 | % | ~33.3 | % | Urinary excretion; PO, oral; | DRUGBANK |
| Protein Binding | 99.0 | % | >99 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 1000.0 | mg/day | 1000 | mg/day | PO, oral | Alinia | nitazoxanide | PDR |
| Max dose for children | 400.0 | mg/day | 400 | mg/day | PO, oral | Alinia | nitazoxanide | PDR |
| Max dose for children | 200.0 | mg/day | 200 | mg/day | PO, oral | Alinia | nitazoxanide | PDR |
| Max dose for adolescents | 1000.0 | mg/day | 1000 | mg/day | PO, oral | Alinia | nitazoxanide | PDR |
| Max dose for adults | 4000.0 | mg/dose | 4000 | mg/dose | Tablet,PO，oral | Alinia | nitazoxanide | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1