Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD00498 ...
Drug Name Phenindione
Molecular Weight 222.2387
Molecular Formula C15H10O2
CAS Number 83-12-5
SMILES O=C1C(C(=O)C2=CC=CC=C12)C1=CC=CC=C1
External Links
DRUGBANK DB00498
T3DB T3D3107
PubChem Compound 4760

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 2.9 - 2.9 - HANSCH,C ET AL. (1995)
Melting Point 150.0 ℃ 150 ℃ PhysProp
Water Solubility 27.0 mg/L 27 mg/L DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Half-life 7.5 h 5-10 h DRUGBANK
Toxicity LD50 175.0 mg/kg 175.0 mg/kg PO, oral; mouse; DRUGBANK
Toxicity LD50 163.0 mg/kg 163.0 mg/kg PO, oral; Rattus, Rat; DRUGBANK
Toxicity LD50 175.0 mg/kg 175.0 mg/kg PO, oral; mouse; T3DB
Toxicity LD50 163.0 mg/kg 163.0 mg/kg PO, oral; Rattus, Rat; T3DB
Protein Binding 88.0 % 88 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1