Basic Information
| Drug ID | DDPD00492 |
|
| Drug Name | Fosinopril | |
| Molecular Weight | 563.672 | |
| Molecular Formula | C30H46NO7P | |
| CAS Number | 98048-97-6 | |
| SMILES | CCC(=O)O[C@@H](O[P@](=O)(CCCCC1=CC=CC=C1)CC(=O)N1C[C@@H](C[C@H]1C(O)=O)C1CCCCC1)C(C)C | |
| External Links | ||
| DRUGBANK | DB00492 | |
| PubChem Compound | 55891 | |
| PDR | 3328 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 6.3 | - | 6.3 | - | DRUGBANK |
| Melting Point | 151.0 | ℃ | 149-153 | ℃ | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 36.0 | % | 36.0 | % | DRUGBANK | |
| Clearance | 2.0 | L/h | 26-39 | ml/min | normal,healthy; | DRUGBANK |
| Half-life | 12.0 | h | 12 | h | DRUGBANK | |
| Protein Binding | 95.0 | % | 95 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 40.0 | mg/day | 40 | mg/day | PO, oral | Fosinopril Sodium | fosinopril sodium | PDR |
| Max dose for adolescents | 40.0 | mg/day | 40 | mg/day | PO, oral | Fosinopril Sodium | fosinopril sodium | PDR |
| Max dose for adults | 80.0 | mg/day | 80 | mg/day | PO, oral | Fosinopril Sodium | fosinopril sodium | PDR |
| Max dose for adults | 40.0 | mg/day | 40 | mg/day | PO, oral | Fosinopril Sodium | fosinopril sodium | PDR |
| Max dose for geriatric | 80.0 | mg/day | 80 | mg/day | PO, oral | Fosinopril Sodium | fosinopril sodium | PDR |
| Max dose for geriatric | 40.0 | mg/day | 40 | mg/day | PO, oral | Fosinopril Sodium | fosinopril sodium | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1