Basic Information
| Drug ID | DDPD00488 |
|
| Drug Name | Altretamine | |
| Molecular Weight | 210.2794 | |
| Molecular Formula | C9H18N6 | |
| CAS Number | 645-05-6 | |
| SMILES | CN(C)C1=NC(=NC(=N1)N(C)C)N(C)C | |
| External Links | ||
| DRUGBANK | DB00488 | |
| PubChem Compound | 2123 | |
| PDR | 2233 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.73 | - | 2.73 | - | HANSCH,C ET AL. (1995) |
| Melting Point | 168.0 | ℃ | 168 | ℃ | von Brachel, H. and Kindler, H.; U.S. Patent 3,424,752; January 28, 1969; assigned to Casella Farbwerke Mainkur AG |
| Water Solubility | 91.0 | mg/L | 91 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 7.5 | h | 4.7-10.2 | h | DRUGBANK | |
| Protein Binding | 94.0 | % | 94 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 260.0 | mg/m2/day | 260 | mg/m2/day | PO, oral | Hexalen | altretamine | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1