Basic Information
| Drug ID | DDPD00486 |
|
| Drug Name | Nabilone | |
| Molecular Weight | 372.5408 | |
| Molecular Formula | C24H36O3 | |
| CAS Number | 51022-71-0 | |
| SMILES | [H][C@@]12CC(=O)CC[C@@]1([H])C(C)(C)OC1=CC(=CC(O)=C21)C(C)(C)CCCCCC | |
| External Links | ||
| DRUGBANK | DB00486 | |
| PubChem Compound | 5284592 | |
| PDR | 692 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 6.8 | - | 6.8 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 100.0 | % | 100.0 | % | PO, oral; | DRUGBANK |
| C Max | 2.0 | ng/ml | ~2 | ng/ml | PO, oral; | DRUGBANK |
| Volume of Distribution | 12.5 | L/kg | 12.5 | L/kg | Apparent volume of distribution; | DRUGBANK |
| Half-life | 2.0 | h | 2 | h | elimination half-life; | DRUGBANK | Half-life | 35.0 | h | 35 | h | elimination half-life; | DRUGBANK |
| Eliminate Route | 67.0 | % | ~67 | % | Faeces excretion; intravenous injection, IV; | DRUGBANK | Eliminate Route | 22.0 | % | ~22 | % | Urinary excretion; intravenous injection, IV; | DRUGBANK | Eliminate Route | 60.0 | % | ~60 | % | Faeces excretion; PO, oral; | DRUGBANK | Eliminate Route | 24.0 | % | ~24 | % | Urinary excretion; PO, oral; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 3.0 | mg/day | 3 | mg/day | PO, oral | Cesamet | nabilone | PDR |
| Max dose for children | 2.0 | mg/day | 2 | mg/day | PO, oral | Cesamet | nabilone | PDR |
| Max dose for children | 1.0 | mg/day | 1 | mg/day | PO, oral | Cesamet | nabilone | PDR |
| Max dose for adolescents | 3.0 | mg/day | 3 | mg/day | PO, oral | Cesamet | nabilone | PDR |
| Max dose for adults | 6.0 | mg/day | 6 | mg/day | PO, oral | Cesamet | nabilone | PDR |
| Max dose for geriatric | 6.0 | mg/day | 6 | mg/day | PO, oral | Cesamet | nabilone | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1