Basic Information
| Drug ID | DDPD00480 |
|
| Drug Name | Lenalidomide | |
| Molecular Weight | 259.2606 | |
| Molecular Formula | C13H13N3O3 | |
| CAS Number | 191732-72-6 | |
| SMILES | NC1=CC=CC2=C1CN(C1CCC(=O)NC1=O)C2=O | |
| External Links | ||
| DRUGBANK | DB00480 | |
| PubChem Compound | 216326 | |
| PDR | 794 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -0.4 | - | -0.4 | - | DRUGBANK |
| Water Solubility | 450.0 | mg/L | 0.4-0.5 | mg/ml | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| T Max | 1.1 | h | 0.625-1.5 | h | PO, oral; | DRUGBANK |
| Half-life | 3.0 | h | 3 | h | normal,healthy; | DRUGBANK | Half-life | 4.0 | h | 3-5 | h | multiple myeloma; | DRUGBANK | Half-life | 4.0 | h | 3-5 | h | Myelodysplastic syndromes; | DRUGBANK |
| Eliminate Route | 90.0 | % | 90 | % | Urinary excretion; Oral single dose; normal,healthy; human, homo sapiens; | DRUGBANK | Eliminate Route | 4.0 | % | 4 | % | Faeces excretion; Oral single dose; normal,healthy; human, homo sapiens; | DRUGBANK |
| Protein Binding | 30.0 | % | 30 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 25.0 | mg/day | 25 | mg/day | PO, oral | Revlimid | lenalidomide | PDR |
| Max dose for geriatric | 25.0 | mg/day | 25 | mg/day | PO, oral | Revlimid | lenalidomide | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1