Basic Information
| Drug ID | DDPD00474 |
|
| Drug Name | Methohexital | |
| Molecular Weight | 262.3043 | |
| Molecular Formula | C14H18N2O3 | |
| CAS Number | 151-83-7 | |
| SMILES | CCC#CC(C)C1(CC=C)C(=O)NC(=O)N(C)C1=O | |
| External Links | ||
| DRUGBANK | DB00474 | |
| T3DB | T3D2803 | |
| PubChem Compound | 9034 | |
| PDR | 1769 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 1.8 | - | 1.8 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 17.0 | % | 17.0 | % | DRUGBANK | |
| Clearance | 0.72 | L/h/kg | 12 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 1.1 | L/kg | 1.1 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 0.0933 | h | 5.6±2.7 | min | DRUGBANK | Half-life | 1.6 | h | 1.6 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Protein Binding | 73.0 | % | 73 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1