Basic Information
| Drug ID | DDPD00467 |
|
| Drug Name | Enoxacin | |
| Molecular Weight | 320.3189 | |
| Molecular Formula | C15H17FN4O3 | |
| CAS Number | 74011-58-8 | |
| SMILES | CCN1C=C(C(O)=O)C(=O)C2=CC(F)=C(N=C12)N1CCNCC1 | |
| External Links | ||
| DRUGBANK | DB00467 | |
| PubChem Compound | 3229 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -0.2 | - | -0.2 | - | SANGSTER (1994) (ION-CORRECT) |
| Melting Point | 222.0 | ℃ | 220-224 | ℃ | PhysProp |
| Water Solubility | 3430.0 | mg/L | 3.43 | g/L | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 90.0 | % | 90.0 | % | PO, oral; | DRUGBANK |
| Clearance | 0.32 | L/h/kg | 5.4 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 2.0 | L/kg | 2 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 4.5 | h | 3-6 | h | elimination half-life; | DRUGBANK | Half-life | 5.1 | h | 5.1 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Protein Binding | 40.0 | % | ~40 | % | plasma proteins; normal,healthy; human, homo sapiens; | DRUGBANK | Protein Binding | 14.0 | % | ~14 | % | plasma proteins; renal insufficiency; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1