| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
| T Max |
7.0 |
h |
3-11 |
h |
PO, oral; |
DRUGBANK |
T Max |
10.5 |
h |
9-12 |
h |
PO, oral; different study; |
DRUGBANK |
| Clearance |
1.5 |
L/h |
20-30 |
ml/min |
|
DRUGBANK |
| Volume of Distribution |
53.0 |
L |
53.0 |
L |
|
DRUGBANK |
| Half-life |
24.0 |
h |
24(19-36) |
h |
|
DRUGBANK |
| Toxicity LD50 |
4290.0 |
mg/kg |
4290.0 |
mg/kg |
PO, oral; mouse; |
DRUGBANK |
Toxicity LD50 |
2380.0 |
mg/kg |
2380.0 |
mg/kg |
Intraperitoneal, IP; mouse; |
DRUGBANK |
Toxicity LD50 |
3880.0 |
mg/kg |
3880.0 |
mg/kg |
PO, oral; Rattus, Rat; |
DRUGBANK |
Toxicity LD50 |
1520.0 |
mg/kg |
1520.0 |
mg/kg |
Intraperitoneal, IP; Rattus, Rat; |
DRUGBANK |
Toxicity LD50 |
10000.0 |
mg/kg |
>10 |
g/kg |
subcutaneous injection, SC; Rattus, Rat; |
DRUGBANK |
Toxicity LD50 |
3200.0 |
mg/kg |
3200.0 |
mg/kg |
PO, oral; monkey; |
DRUGBANK |
| Eliminate Route |
80.0 |
% |
80 |
% |
Urinary excretion; |
DRUGBANK |
Eliminate Route |
10.0 |
% |
10 |
% |
Faeces excretion; |
DRUGBANK |
| Protein Binding |
99.0 |
% |
<99 |
% |
plasma proteins; |
DRUGBANK |
