Basic Information
| Drug ID | DDPD00460 |
|
| Drug Name | Verteporfin | |
| Molecular Weight | 718.7942 | |
| Molecular Formula | C41H42N4O8 | |
| CAS Number | 129497-78-5 | |
| SMILES | COC(=O)CCC1=C2NC(\C=C3/N=C(/C=C4\N\C(=C/C5=N/C(=C\2)/C(CCC(O)=O)=C5C)C(C=C)=C4C)C2=CC=C([C@@H](C(=O)OC)[C@@]32C)C(=O)OC)=C1C | |
| External Links | ||
| DRUGBANK | DB00460 | |
| PubChem Compound | 5362420 | |
| PDR | 651 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.1 | - | 2.1 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 5.5 | h | ~5-6 | h | elimination half-life; intravenous infusion, IV in drop; | DRUGBANK | Half-life | 6.6 | h | ~6-7.2 | h | mild hepatic impairment; | DRUGBANK |
| Eliminate Route | 0.0100 | % | <0.01 | % | Urinary excretion; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 6.0 | mg/m2 | 6 | mg/m2 | intravenous injection, IV | Visudyne | verteporfin | PDR |
| Max dose for elderly | 6.0 | mg/m2 | 6 | mg/m2 | intravenous injection, IV | Visudyne | verteporfin | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1