DETAILS

Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID	DDPD00456
Drug Name	Cefalotin
Molecular Weight	396.438
Molecular Formula	C16H16N2O6S2
CAS Number	153-61-7
SMILES	[H][C@@]1(NC(=O)CC2=CC=CS2)C(=O)N2C(C(O)=O)=C(COC(C)=O)CS[C@]12[H]
External Links
	DRUGBANK	DB00456
	PubChem Compound	6024

Experimental Physicochemical Property

Property Name	Property Value	Unit	Raw Value	Raw Unit	Reference
Log P	0.0	-	0.0	-	HANSCH,C ET AL. (1995)
Melting Point	160.25	℃	160-160.5	℃	PhysProp
Water Solubility	158.0	mg/L	158	mg/L	DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name	Property Value	Unit	Raw Value	Raw Unit	Annotation	Reference
Metabolic	62.5	%	50-75	%	Urinary excretion;	DRUGBANK
Half-life	0.50	h	30	min		DRUGBANK
Toxicity LD50	4000.0	mg/kg	4000.0	mg/kg	intravenous injection, IV; Rattus, Rat;	DRUGBANK
Protein Binding	72.5	%	65-80	%		DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1