Basic Information
| Drug ID | DDPD00439 |
|
| Drug Name | Cerivastatin | |
| Molecular Weight | 459.5503 | |
| Molecular Formula | C26H34FNO5 | |
| CAS Number | 145599-86-6 | |
| SMILES | COCC1=C(C2=CC=C(F)C=C2)C(\C=C\[C@@H](O)C[C@@H](O)CC(O)=O)=C(C(C)C)N=C1C(C)C | |
| External Links | ||
| DRUGBANK | DB00439 | |
| PubChem Compound | 446156 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.4 | - | 3.4 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 60.0 | % | 60(39-101) | % | DRUGBANK | |
| Clearance | 0.17 | L/h/kg | 2.9 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.33 | L/kg | 0.33 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 2.5 | h | 2-3 | h | DRUGBANK | Half-life | 1.8 | h | 1.8 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Protein Binding | 99.0 | % | >99 | % | plasma proteins; | DRUGBANK | Protein Binding | 80.0 | % | 80 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1