Basic Information
| Drug ID | DDPD00436 |
|
| Drug Name | Bendroflumethiazide | |
| Molecular Weight | 421.415 | |
| Molecular Formula | C15H14F3N3O4S2 | |
| CAS Number | 73-48-3 | |
| SMILES | NS(=O)(=O)C1=CC2=C(NC(CC3=CC=CC=C3)NS2(=O)=O)C=C1C(F)(F)F | |
| External Links | ||
| DRUGBANK | DB00436 | |
| PubChem Compound | 2315 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 1.89 | - | 1.89 | - | BERTHOD,A ET AL. (1999) |
| Melting Point | 222.5 | ℃ | 222-223 | ℃ | Goldberg, M.; U.S. Patent 3,265,573; August 9, 1966; assigned to E.R. Squibb & Sons, Inc. Lund, F., Lyngby, K. and Godtfredsen, W.O.; U.S. Patent 3,392,168; July 9, 1968; assigned to Lovens Kemiske Fabrik ved A. Kongsted, Denmark. |
| Water Solubility | 108.0 | mg/L | 108 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
| pKa | 8.5 | - | 8.5 | - | SANGSTER (1994) |
| Log S | -3.59 | - | -3.59 | - | ADME Research, USCD |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 8.5 | h | 8.5 | h | at steady state; | DRUGBANK |
| Protein Binding | 96.0 | % | 96 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1