Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD00431 ...
Drug Name Lindane
Molecular Weight 290.83
Molecular Formula C6H6Cl6
CAS Number 58-89-9
SMILES Cl[C@H]1[C@H](Cl)[C@@H](Cl)[C@@H](Cl)[C@H](Cl)[C@H]1Cl
External Links
DRUGBANK DB00431
T3DB T3D0032
ATSDR ATSDR Page
PubChem Compound 727
PDR 654
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 3.72 - 3.72 - HANSCH,C ET AL. (1995)
Boiling Point 323.4 ℃ 323.4 ℃ PhysProp
Melting Point 112.5 ℃ 112.5 ℃ PhysProp
Water Solubility 7.3 mg/L 7.3 mg/L RICHARDSON,LT & MILLER,DM 1960)

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
C Max 28.0 ng/ml 28.0 ng/ml skin/dermal; DRUGBANK
T Max 6.0 h 6 h skin/dermal; DRUGBANK
Half-life 18.0 h 18 h DRUGBANK
Toxicity LD50 139.0 mg/kg 88-190 mg/kg PO, oral; Rattus, Rat; DRUGBANK
Toxicity LD50 750.0 mg/kg 500-1000 mg/kg skin/dermal; Isomers; Rattus, Rat; DRUGBANK
Toxicity LD50 300.0 mg/kg 300.0 mg/kg skin/dermal; Isomers; mouse; DRUGBANK
Toxicity LD50 400.0 mg/kg 400.0 mg/kg skin/dermal; Isomers; guinea pigs; DRUGBANK
Toxicity LD50 300.0 mg/kg 300.0 mg/kg skin/dermal; Isomers; rabbit; DRUGBANK
Toxicity LD50 139.0 mg/kg 88-190 mg/kg PO, oral; Rattus, Rat; T3DB
Toxicity LD50 750.0 mg/kg 500-1000 mg/kg skin/dermal; Rattus, Rat; T3DB
Toxicity LD50 300.0 mg/kg 300.0 mg/kg skin/dermal; mouse; T3DB
Toxicity LD50 400.0 mg/kg 400.0 mg/kg skin/dermal; guinea pigs; T3DB
Toxicity LD50 300.0 mg/kg 300.0 mg/kg skin/dermal; rabbit; T3DB
Toxicity LD50 76.0 mg/kg 76.0 mg/kg PO, oral; Rattus, Rat; T3DB
Toxicity LD50 50.0 mg/kg 50.0 mg/kg skin/dermal; rabbit; T3DB
Toxicity LD50 125.0 mg/kg 125.0 mg/kg Intraperitoneal, IP; mouse; T3DB
Toxicity Lethal Dose 28000.0 mg 28.0 g adults; human, homo sapiens; T3DB
Toxicity MRLs 0.003000 mg/kg/day 0.003 mg/kg/day PO, oral; ATSDR
Toxicity MRLs 0.000010 mg/kg/day 1e-05 mg/kg/day PO, oral; ATSDR
Toxicity MRLs 0.003000 mg/kg/day 0.003 mg/kg/day PO, oral; T3DB
Toxicity MRLs 0.000010 mg/kg/day 1e-05 mg/kg/day PO, oral; T3DB
Protein Binding 91.0 % 91 % DRUGBANK

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for infants 0.0 0 Lindane Lotion lindane PDR
Max dose for children 60.0 ml 60 ml skin/dermal Lindane Lotion lindane PDR
Max dose for children 0.0 0 skin/dermal Lindane Lotion lindane PDR
Max dose for adolescents 60.0 ml 60 ml skin/dermal Lindane Lotion lindane PDR
Max dose for adolescents 0.0 0 skin/dermal Lindane Lotion lindane PDR
Max dose for adults 60.0 ml 60 ml skin/dermal Lindane Lotion lindane PDR
Max dose for adults 0.0 0 skin/dermal Lindane Lotion lindane PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1