Basic Information
| Drug ID | DDPD00428 |
|
| Drug Name | Streptozocin | |
| Molecular Weight | 265.2206 | |
| Molecular Formula | C8H15N3O7 | |
| CAS Number | 18883-66-4 | |
| SMILES | CN(N=O)C(=O)N[C@H]1[C@@H](O)O[C@H](CO)[C@@H](O)[C@@H]1O | |
| External Links | ||
| DRUGBANK | DB00428 | |
| T3DB | T3D2788 | |
| PubChem Compound | 29327 | |
| PDR | 812 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -1.45 | - | -1.45 | - | HANSCH,C ET AL. (1995) |
| Melting Point | 115.0 | ℃ | 115 | ℃ | PhysProp |
| Water Solubility | 5070.0 | mg/L | 5070 | mg/L | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 21.0 | % | 17-25 | % | PO, oral; | DRUGBANK |
| Half-life | 0.17 | h | 5-15 | min | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 1500.0 | mg/m2/dose | 1500 | mg/m2/dose | intravenous injection, IV | Zanosar | streptozocin | PDR |
| Max dose for adolescents | 1500.0 | mg/m2/dose | 1500 | mg/m2/dose | intravenous injection, IV | Zanosar | streptozocin | PDR |
| Max dose for adults | 1500.0 | mg/m2/dose | 1500 | mg/m2/dose | intravenous injection, IV | Zanosar | streptozocin | PDR |
| Max dose for elderly | 1500.0 | mg/m2/dose | 1500 | mg/m2/dose | intravenous injection, IV | Zanosar | streptozocin | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1