Basic Information
| Drug ID | DDPD00426 |
|
| Drug Name | Famciclovir | |
| Molecular Weight | 321.3318 | |
| Molecular Formula | C14H19N5O4 | |
| CAS Number | 104227-87-4 | |
| SMILES | CC(=O)OCC(CCN1C=NC2=CN=C(N)N=C12)COC(C)=O | |
| External Links | ||
| DRUGBANK | DB00426 | |
| PubChem Compound | 3324 | |
| PDR | 1802 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 0.6 | - | 0.6 | - | DRUGBANK |
| Melting Point | 103.0 | ℃ | 102-104 | ℃ | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 77.0 | % | 77.0 | % | DRUGBANK | |
| Clearance | 36.6 | L/h | 36.6±6.3 | L/h | DRUGBANK | Clearance | 0.48 | L/h/kg | 0.48±0.09 | L/h/kg | DRUGBANK |
| Volume of Distribution | 1.1 | L/kg | 1.08±0.17 | L/kg | normal,healthy; Male, men; | DRUGBANK |
| Half-life | 10.0 | h | 10 | h | DRUGBANK | |
| Protein Binding | 22.5 | % | 20-25 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 2000.0 | mg/day | 2000 | mg/day | PO, oral | Famvir | famciclovir | PDR |
| Max dose for adults | 1500.0 | mg/day | 1500 | mg/day | PO, oral | Famvir | famciclovir | PDR |
| Max dose for elderly | 2000.0 | mg/day | 2000 | mg/day | PO, oral | Famvir | famciclovir | PDR |
| Max dose for elderly | 1500.0 | mg/day | 1500 | mg/day | PO, oral | Famvir | famciclovir | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1