| Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
| AUC |
52500.0 |
ng.h/ml |
52.5 |
mg.h/l |
normal,healthy; |
DRUGBANK |
AUC |
87100.0 |
ng.h/ml |
87.1 |
mg.h/l |
|
DRUGBANK |
| C Max |
21300.0 |
ng/ml |
21.3 |
mg/L |
normal,healthy; |
DRUGBANK |
C Max |
28700.0 |
ng/ml |
28.7 |
mg/L |
|
DRUGBANK |
| T Max |
1.1 |
h |
1.1 |
h |
normal,healthy; |
DRUGBANK |
T Max |
1.1 |
h |
1.1 |
h |
|
DRUGBANK |
T Max |
0.50 |
h |
0.5 |
h |
different study; |
DRUGBANK |
| Clearance |
0.50 |
L/h/kg |
0.2-0.8 |
L/h/kg |
|
DRUGBANK |
| Volume of Distribution |
0.73 |
L/kg |
515-942 |
mL/kg |
horse; at steady state; |
DRUGBANK |
| Half-life |
1.1 |
h |
1.14 |
h |
elimination half-life; normal,healthy; |
DRUGBANK |
Half-life |
1.2 |
h |
1.24 |
h |
elimination half-life; renal insufficiency; |
DRUGBANK |
Half-life |
1.9 |
h |
1.6-2.15 |
h |
|
DRUGBANK |
| Toxicity LD50 |
3576.2 |
mg/kg |
3576.2 |
mg/kg |
PO, oral; Rattus, Rat; |
DRUGBANK |
| Eliminate Route |
88.9 |
% |
88.85 |
% |
Urinary excretion; dog; |
DRUGBANK |
Eliminate Route |
2.1 |
% |
2.14 |
% |
Faeces excretion; dog; |
DRUGBANK |
Eliminate Route |
88.5 |
% |
84.5-92.5 |
% |
Urinary excretion; Rattus, Rat; |
DRUGBANK |
Eliminate Route |
6.7 |
% |
0-13.3 |
% |
Faeces excretion; Rattus, Rat; |
DRUGBANK |
| Protein Binding |
0 |
% |
46-50 |
% |
normal,healthy; patients; |
DRUGBANK |
Protein Binding |
48.1 |
% |
47.3-48.9 |
% |
|
DRUGBANK |
