Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 4.55 | - | 4.55 | - | HANSCH,C ET AL. (1995) |
| Boiling Point | 206.5 | ℃ | 203-210 | ℃ | PhysProp |
| Melting Point | 25.0 | ℃ | <25 | ℃ | PhysProp |
| Water Solubility | 14.2 | mg/L | 14.2 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
| pKa | 9.36 | - | 9.36 | - | SANGSTER (1994) |
| Log S | -4.3 | - | -4.3 | - | ADME Research, USCD |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.84 | L/h/kg | 14 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 8.1 | L/kg | 8.1 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 7.9 | h | 7.9 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Toxicity LD50 | 140.0 | mg/kg | 140.0 | mg/kg | Intraperitoneal, IP; mouse; | T3DB |
| Protein Binding | 94.0 | % | 94 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1