Basic Information
| Drug ID | DDPD00419 |
|
| Drug Name | Miglustat | |
| Molecular Weight | 219.278 | |
| Molecular Formula | C10H21NO4 | |
| CAS Number | 72599-27-0 | |
| SMILES | CCCCN1C[C@H](O)[C@@H](O)[C@H](O)[C@H]1CO | |
| External Links | ||
| DRUGBANK | DB00419 | |
| PubChem Compound | 51634 | |
| PDR | 1375 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -0.6 | - | -0.6 | - | DRUGBANK |
| Melting Point | 170.5 | ℃ | 169-172 | ℃ | DRUGBANK |
| Water Solubility | 1000000.0 | mg/L | >1000 | mg/ml | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 97.0 | % | 97.0 | % | PO, oral; | DRUGBANK |
| Metabolic | 0 | % | 0 | % | DRUGBANK | |
| Half-life | 6.5 | h | ~6-7 | h | effective half-life; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 300.0 | mg/day | 300 | mg/day | PO, oral | Zavesca | miglustat | PDR |
| Max dose for geriatric | 300.0 | mg/day | 300 | mg/day | PO, oral | Zavesca | miglustat | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1