Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD00415 ...
Drug Name Ampicillin
Molecular Weight 349.405
Molecular Formula C16H19N3O4S
CAS Number 69-53-4
SMILES [H][C@]12SC(C)(C)[C@@H](N1C(=O)[C@H]2NC(=O)[C@H](N)C1=CC=CC=C1)C(O)=O
External Links
DRUGBANK DB00415
PubChem Compound 6249
PDR 2424
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P 1.35 - 1.35 - SANGSTER (1994)
Melting Point 208.0 ℃ 208 ℃ PhysProp
Water Solubility 10100.0 mg/L 10100 mg/L YALKOWSKY,SH & DANNENFELSER,RM 1992)

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 0.17 L/h/kg 2.8 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 0.22 L/kg 0.22 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 1.4 h 1.4 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for neonates 150.0 mg/kg/day 150 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for neonates 300.0 mg/kg/day 300 mg/kg/day intravenous injection, IV Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for neonates 150.0 mg/kg/day 150 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for neonates 300.0 mg/kg/day 300 mg/kg/day intravenous injection, IV Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for neonates 100.0 mg/kg/day 100 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for neonates 300.0 mg/kg/day 300 mg/kg/day intravenous injection, IV Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for infants 100.0 mg/kg/day 100 mg/kg/day PO, oral Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for infants 200.0 mg/kg/day 200 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for infants 400.0 mg/kg/day 400 mg/kg/day intravenous injection, IV Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for children 100.0 mg/kg/day 100 mg/kg/day PO, oral Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for children 2000.0 mg/day 2 g/day PO, oral Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for children 200.0 mg/kg/day 200 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for children 400.0 mg/kg/day 400 mg/kg/day intravenous injection, IV Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for children 12000.0 mg/day 12 g/day intravenous injection, IV Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for adolescents 100.0 mg/kg/day 100 mg/kg/day PO, oral Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for adolescents 2000.0 mg/day 2 g/day PO, oral Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for adolescents 200.0 mg/kg/day 200 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for adolescents 400.0 mg/kg/day 400 mg/kg/day intravenous injection, IV Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for adolescents 12000.0 mg/day 12 g/day intravenous injection, IV Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for adults 2000.0 mg/day 2 g/day PO, oral Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for adults 200.0 mg/kg/day 200 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for adults 12000.0 mg/day 12 g/day intravenous injection, IV;IM,intramuscular injection; Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for geriatric 2000.0 mg/day 2 g/day PO, oral Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for geriatric 200.0 mg/kg/day 200 mg/kg/day intravenous injection, IV;IM,intramuscular injection; Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR
Max dose for geriatric 12000.0 mg/day 12 g/day intravenous injection, IV;IM,intramuscular injection; Ampicillin Capsules and Oral Suspension ampicillin trihydrate PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1