Basic Information
| Drug ID | DDPD00414 |
|
| Drug Name | Acetohexamide | |
| Molecular Weight | 324.395 | |
| Molecular Formula | C15H20N2O4S | |
| CAS Number | 968-81-0 | |
| SMILES | CC(=O)C1=CC=C(C=C1)S(=O)(=O)NC(=O)NC1CCCCC1 | |
| External Links | ||
| DRUGBANK | DB00414 | |
| PubChem Compound | 1989 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.44 | - | 2.44 | - | SANGSTER (1993) |
| Melting Point | 189.0 | ℃ | 188-190 | ℃ | Sigal,M.V.,Jr.andVanArendonk,A.M.; US.Patent3,320,312;May16,1967;assigned to Eli Lilly and Company. |
| Water Solubility | 3430.0 | mg/L | 3430 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
| Log S | -2.06 | - | -2.06 | - | ADME Research, USCD |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 1.3 | h | 1.3 | h | elimination half-life; | DRUGBANK | Half-life | 5.5 | h | ~5-6 | h | Active metabolite; | DRUGBANK |
| Toxicity LD50 | 5000.0 | mg/kg | 5.0 | g/kg | PO, oral; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 2500.0 | mg/kg | >2500 | mg/kg | PO, oral; mouse; | DRUGBANK |
| Protein Binding | 90.0 | % | 90 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1