Basic Information
| Drug ID | DDPD00410 |
|
| Drug Name | Mupirocin | |
| Molecular Weight | 500.6222 | |
| Molecular Formula | C26H44O9 | |
| CAS Number | 12650-69-0 | |
| SMILES | C[C@H](O)[C@H](C)[C@@H]1O[C@H]1C[C@H]1CO[C@@H](C\C(C)=C\C(=O)OCCCCCCCCC(O)=O)[C@H](O)[C@@H]1O | |
| External Links | ||
| DRUGBANK | DB00410 | |
| PubChem Compound | 446596 | |
| PDR | 2207 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Melting Point | 77.5 | ℃ | 77-78 | ℃ | MSDS |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 0.50 | h | ~20-40 | min | elimination half-life; intravenous injection, IV; normal,healthy; Male, men; | DRUGBANK | Half-life | 0.92 | h | ~30-80 | min | elimination half-life; | DRUGBANK |
| Toxicity LD50 | 5000.0 | mg/kg | 5000.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK |
| Protein Binding | 95.0 | % | >95 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Frequency | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|---|
| Max dose for children | 5.0 | days | 5 | days | nasal spray | bid | Bactroban Cream | mupirocin calcium | PDR |
| Max dose for adolescents | 5.0 | days | 5 | days | nasal spray | bid | Bactroban Cream | mupirocin calcium | PDR |
| Max dose for adults | 5.0 | days | 5 | days | nasal spray | bid | Bactroban Cream | mupirocin calcium | PDR |
| Max dose for geriatric | 5.0 | days | 5 | days | nasal spray | bid | Bactroban Cream | mupirocin calcium | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1