Basic Information
| Drug ID | DDPD00395 |
|
| Drug Name | Carisoprodol | |
| Molecular Weight | 260.33 | |
| Molecular Formula | C12H24N2O4 | |
| CAS Number | 78-44-4 | |
| SMILES | CCCC(C)(COC(N)=O)COC(=O)NC(C)C | |
| External Links | ||
| DRUGBANK | DB00395 | |
| T3DB | T3D3491 | |
| PubChem Compound | 2576 | |
| PDR | 2128 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.1 | - | 2.1 | - | http://www.t3db.ca/toxins/T3D3491 |
| Boiling Point | 423.412 | ℃ | 423.412 | ℃ | https://www.lookchem.com/Carisoprodol/ |
| Melting Point | 92.0 | ℃ | 92 | ℃ | https://www.lookchem.com/Carisoprodol/ |
| pKa | 15.06 | - | 15.06 | - | http://www.t3db.ca/toxins/T3D3491 |
| Log S | -2.5 | - | -2.5 | - | http://www.t3db.ca/toxins/T3D3491 |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Factor | Reference |
|---|---|---|---|---|---|---|---|
| T Max | 1.8 | h | 1.5-2 | h | high-fat meal; | high-fat meal → ; | DRUGBANK |
| Clearance | 39.5 | L/h | 39.52±16.83 | L/h | PO, oral; | DRUGBANK | |
| Volume of Distribution | 1.1 | L/kg | 0.93-1.3 | L/kg | DRUGBANK | ||
| Half-life | 2.0 | h | ~2 | h | terminal half-life; | DRUGBANK | |
| Toxicity LD50 | 450.0 | mg/kg | 450.0 | mg/kg | intravenous injection, IV; Intraperitoneal, IP; Rattus, Rat; | DRUGBANK | Toxicity LD50 | 1320.0 | mg/kg | 1320.0 | mg/kg | intragastric; | DRUGBANK | Toxicity LD50 | 165.0 | mg/kg | 165.0 | mg/kg | intravenous injection, IV; mouse; | DRUGBANK | Toxicity LD50 | 980.0 | mg/kg | 980.0 | mg/kg | Intraperitoneal, IP; mouse; | DRUGBANK | Toxicity LD50 | 2340.0 | mg/kg | 2340.0 | mg/kg | intragastric; | DRUGBANK | Toxicity LD50 | 124.0 | mg/kg | 124.0 | mg/kg | intravenous injection, IV; rabbit; | DRUGBANK |
| Protein Binding | 60.0 | % | ~60 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adolescents | 1400.0 | mg/day | 1400 | mg/day | PO, oral | Soma | carisoprodol | PDR |
| Max dose for adults | 1400.0 | mg/day | 1400 | mg/day | PO, oral | Soma | carisoprodol | PDR |
| Max dose for geriatric | 1400.0 | mg/day | 1400 | mg/day | PO, oral | Soma | carisoprodol | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1