Basic Information
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Caco-2 Permeability | -6.16 | - | -6.16 | - | ADME Research, USCD |
| Log P | 0.57 | - | 0.57 | - | HOEGBERG,T ET AL. 1986 |
| Melting Point | 178.0 | ℃ | 178 | ℃ | PhysProp |
| Water Solubility | 2280.0 | mg/L | 2280 | mg/L | DRUGBANK |
| pKa | 9.12 | - | 9.12 | - | EL TAYAR,N ET AL. (1985) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 30.0 | % | 25-35 | % | DRUGBANK | |
| Clearance | 0.11 | L/h/kg | 1.9 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.94 | L/kg | 0.94 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 7.0 | h | 6-8 | h | DRUGBANK | Half-life | 6.5 | h | 6.5 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1