Basic Information
| Drug ID | DDPD00385 |
|
| Drug Name | Valrubicin | |
| Molecular Weight | 723.651 | |
| Molecular Formula | C34H36F3NO13 | |
| CAS Number | 56124-62-0 | |
| SMILES | [H][C@@]1(C[C@@](O)(CC2=C(O)C3=C(C(O)=C12)C(=O)C1=C(OC)C=CC=C1C3=O)C(=O)COC(=O)CCCC)O[C@H]1C[C@H](NC(=O)C(F)(F)F)[C@H](O)[C@H](C)O1 | |
| External Links | ||
| DRUGBANK | DB00385 | |
| PubChem Compound | 454216 | |
| PDR | 2810 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.2 | - | 2.2 | - | DRUGBANK |
| Melting Point | 116.5 | ℃ | 116-117 | ℃ | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Toxicity MTD | 600.0 | mg/m2 | 600.0 | mg/m2 | Intraperitoneal, IP; intravenous injection, IV; human, homo sapiens; | DRUGBANK |
| Protein Binding | 99.0 | % | >99 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 800.0 | mg | 800 | mg | intravesically | Valstar | valrubicin | PDR |
| Max dose for elderly | 800.0 | mg | 800 | mg | intravesically | Valstar | valrubicin | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1