Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
Bioavailability |
17.0 |
% |
17.0 |
% |
|
DRUGBANK |
Clearance |
3.4 |
L/h/kg |
56 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Volume of Distribution |
349.0 |
L |
349±193 |
L |
|
DRUGBANK |
Volume of Distribution |
11.0 |
L/kg |
11 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Half-life |
3.0 |
h |
2-4 |
h |
|
DRUGBANK |
Half-life |
3.3 |
h |
3.3 |
h |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Toxicity LD50 |
40.0 |
mg/kg |
40.0 |
mg/kg |
Oral single dose; Rattus, Rat; |
DRUGBANK |
Toxicity MRHD |
160.0 |
mg/day |
160.0 |
mg/day |
|
DRUGBANK |
Toxicity Lethal Dose |
40.0 |
mg/kg |
40.0 |
mg/kg |
Oral single dose; Rattus, Rat; |
T3DB |
Protein Binding |
55.0 |
% |
55 |
% |
|
DRUGBANK |