Basic Information
| Drug ID | DDPD00371 |
|
| Drug Name | Meprobamate | |
| Molecular Weight | 218.2502 | |
| Molecular Formula | C9H18N2O4 | |
| CAS Number | 57-53-4 | |
| SMILES | CCCC(C)(COC(N)=O)COC(N)=O | |
| External Links | ||
| DRUGBANK | DB00371 | |
| PubChem Compound | 4064 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 0.7 | - | 0.7 | - | HANSCH,C ET AL. (1995) |
| Melting Point | 105.0 | ℃ | 105 | ℃ | PhysProp |
| Water Solubility | 4700.0 | mg/L | 4700 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
| Log S | -1.67 | - | -1.67 | - | ADME Research, USCD |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.0360 | L/h/kg | 0.6 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.70 | L/kg | 0.7 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 10.0 | h | ~10 | h | elimination half-life; | DRUGBANK | Half-life | 14.0 | h | 14 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1