Basic Information
| Drug ID | DDPD00364 |
|
| Drug Name | Sucralfate | |
| Molecular Weight | 1558.67 | |
| Molecular Formula | C12H35Al9O55S8 | |
| CAS Number | 54182-58-0 | |
| SMILES | O.O[Al](O)O.O[Al](O)OS(=O)(=O)OC[C@H]1O[C@@](COS(=O)(=O)O[Al](O)O)(O[C@H]2O[C@H](COS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)[C@H](OS(=O)(=O)O[Al](O)O)[C@H]2OS(=O)(=O)O[Al](O)O)[C@@H](OS(=O)(=O)O[Al](O)O)[C@@H]1OS(=O)(=O)O[Al](O)O | |
| External Links | ||
| DRUGBANK | DB00364 | |
| PubChem Compound | 70789197 | |
| PDR | 2163 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -7.087 | - | -7.087 | - | http://www.molbase.com/en/overview_54182-58-0-moldata-62765.html |
| Melting Point | 220.0 | ℃ | >220 | ℃ | https://www.trc-canada.com/product-detail/?S692350 |
| pKa | 0.81 | - | 0.43-1.19 | - | https://www.chemicalbook.com/ChemicalProductProperty_US_CB6239042.aspx |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 0.009000 | % | 0.001-0.017 | % | PO, oral; normal,healthy; | DRUGBANK |
| Half-life | 13.0 | h | 6-20 | h | elimination half-life; animals; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 80.0 | mg/kg/day | 80 | mg/kg/day | PO, oral | Carafate Tablets | sucralfate | PDR |
| Max dose for children | 2000.0 | mg/day | 2000 | mg/day | PO, oral | Carafate Tablets | sucralfate | PDR |
| Max dose for adolescents | 4000.0 | mg/day | 4 | g/day | PO, oral | Carafate Tablets | sucralfate | PDR |
| Max dose for adults | 4000.0 | mg/day | 4 | g/day | PO, oral | Carafate Tablets | sucralfate | PDR |
| Max dose for elderly | 4000.0 | mg/day | 4 | g/day | PO, oral | Carafate Tablets | sucralfate | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1