Basic Information Experimental Physicochemical Property Pharmacokinetic/Toxicokinetic Property Maximum Dosage Drug Property Radar Chart

Basic Information

Drug ID DDPD00360 ...
Drug Name Sapropterin
Molecular Weight 241.2471
Molecular Formula C9H15N5O3
CAS Number 62989-33-7
SMILES [H][C@@]1(CNC2=C(N1)C(=O)NC(N)=N2)[C@@H](O)[C@H](C)O
External Links
DRUGBANK DB00360
PubChem Compound 44257
PDR 2119

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P -1.7 - -1.7 - DRUGBANK
Melting Point 252.5 ℃ 250-255 ℃ DRUGBANK
Water Solubility 20000.0 mg/L >20 mg/ml DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Not Available

Maximum Dosage

Property Name Property Value Unit Raw Value Raw Unit Annotation Brand Name Component Reference
Max dose for infants 20.0 mg/kg/day 20 mg/kg/day Kuvan sapropterin dihydrochloride PDR
Max dose for children 20.0 mg/kg/day 20 mg/kg/day Kuvan sapropterin dihydrochloride PDR
Max dose for adolescents 20.0 mg/kg/day 20 mg/kg/day Kuvan sapropterin dihydrochloride PDR
Max dose for adults 20.0 mg/kg/day 20 mg/kg/day Kuvan sapropterin dihydrochloride PDR

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1