Drug ID | DDPD00359 |
|
Drug Name | Sulfadiazine | |
Molecular Weight | 250.277 | |
Molecular Formula | C10H10N4O2S | |
CAS Number | 68-35-9 | |
SMILES | NC1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=N1 | |
External Links | ||
DRUGBANK | DB00359 | |
PubChem Compound | 5215 | |
Drugs.com | Drugs.com Drug Page |
Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
---|---|---|---|---|---|
Log P | -0.09 | - | -0.09 | - | HANSCH,C ET AL. (1995) |
Melting Point | 255.5 | ℃ | 255.5 | ℃ | PhysProp |
Water Solubility | 77.0 | mg/L | 77 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
pKa | 6.36 | - | 6.36 | - | SANGSTER (1994) |
Log S | -3.51 | - | -3.51 | - | ADME Research, USCD |
Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
---|---|---|---|---|---|---|
Clearance | 0.0330 | L/h/kg | 0.55 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Volume of Distribution | 0.29 | L/kg | 0.29 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Half-life | 7.0 | h | 7 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
Toxicity LD50 | 1500.0 | mg/kg | 1500.0 | mg/kg | PO, oral; mouse; | DRUGBANK |
Not Available