Basic Information
| Drug ID | DDPD00359 |
|
| Drug Name | Sulfadiazine | |
| Molecular Weight | 250.277 | |
| Molecular Formula | C10H10N4O2S | |
| CAS Number | 68-35-9 | |
| SMILES | NC1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=N1 | |
| External Links | ||
| DRUGBANK | DB00359 | |
| PubChem Compound | 5215 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -0.09 | - | -0.09 | - | HANSCH,C ET AL. (1995) |
| Melting Point | 255.5 | ℃ | 255.5 | ℃ | PhysProp |
| Water Solubility | 77.0 | mg/L | 77 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
| pKa | 6.36 | - | 6.36 | - | SANGSTER (1994) |
| Log S | -3.51 | - | -3.51 | - | ADME Research, USCD |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.0330 | L/h/kg | 0.55 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.29 | L/kg | 0.29 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 7.0 | h | 7 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Toxicity LD50 | 1500.0 | mg/kg | 1500.0 | mg/kg | PO, oral; mouse; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1