Basic Information

Drug ID DDPD00359 ...
Drug Name Sulfadiazine
Molecular Weight 250.277
Molecular Formula C10H10N4O2S
CAS Number 68-35-9
SMILES NC1=CC=C(C=C1)S(=O)(=O)NC1=NC=CC=N1
External Links
DRUGBANK DB00359
PubChem Compound 5215
Drugs.com Drugs.com Drug Page

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P -0.09 - -0.09 - HANSCH,C ET AL. (1995)
Melting Point 255.5 255.5 PhysProp
Water Solubility 77.0 mg/L 77 mg/L YALKOWSKY,SH & DANNENFELSER,RM 1992)
pKa 6.36 - 6.36 - SANGSTER (1994)
Log S -3.51 - -3.51 - ADME Research, USCD

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 0.0330 L/h/kg 0.55 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 0.29 L/kg 0.29 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 7.0 h 7 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Toxicity LD50 1500.0 mg/kg 1500.0 mg/kg PO, oral; mouse; DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1