Basic Information
| Drug ID | DDPD00356 |
|
| Drug Name | Chlorzoxazone | |
| Molecular Weight | 169.565 | |
| Molecular Formula | C7H4ClNO2 | |
| CAS Number | 95-25-0 | |
| SMILES | ClC1=CC2=C(OC(=O)N2)C=C1 | |
| External Links | ||
| DRUGBANK | DB00356 | |
| PubChem Compound | 2733 | |
| PDR | 3750 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 1.6 | - | 1.6 | - | DRUGBANK |
| Melting Point | 191.25 | ℃ | 191-191.5 | ℃ | Marsh, D.F.; US. Patent 2,895,877; July 21, 1959; assigned to McNeil Laboratories, Inc. |
| Water Solubility | 1000.0 | mg/L | 1000 | mg/L | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Toxicity LD50 | 440.0 | mg/kg | 440.0 | mg/kg | PO, oral; mouse; | DRUGBANK | Toxicity LD50 | 763.0 | mg/kg | 763.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK |
| Protein Binding | 15.5 | % | 13-18 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 3000.0 | mg/day | 3000 | mg/day | PO, oral | Lorzone | chlorzoxazone | PDR |
| Max dose for geriatric | 3000.0 | mg/day | 3000 | mg/day | PO, oral | Lorzone | chlorzoxazone | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1