Basic Information
| Drug ID | DDPD00352 |
|
| Drug Name | Tioguanine | |
| Molecular Weight | 167.192 | |
| Molecular Formula | C5H5N5S | |
| CAS Number | 154-42-7 | |
| SMILES | NC1=NC(=S)C2=C(N1)N=CN2 | |
| External Links | ||
| DRUGBANK | DB00352 | |
| T3DB | T3D4770 | |
| PubChem Compound | 2723601 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -0.07 | - | -0.07 | - | HANSCH,C ET AL. (1995) |
| Melting Point | 360.0 | ℃ | >360 | ℃ | PhysProp |
| Water Solubility | 36300.0 | mg/L | 36.3 | mg/ml | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 30.0 | % | 30(14-46) | % | PO, oral; | DRUGBANK |
| Half-life | 0.13 | h | 80(25-240) | min | elimination half-life; Single dose; | DRUGBANK |
| Toxicity LD50 | 160.0 | mg/kg | 160.0 | mg/kg | PO, oral; mouse; | DRUGBANK | Toxicity LD50 | 160.0 | mg/kg | 160.0 | mg/kg | PO, oral; mouse; | T3DB |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1