Basic Information
| Drug ID | DDPD00351 |
|
| Drug Name | Megestrol acetate | |
| Molecular Weight | 384.516 | |
| Molecular Formula | C24H32O4 | |
| CAS Number | 595-33-5 | |
| SMILES | [H][C@@]12CC[C@](OC(C)=O)(C(C)=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])C=C(C)C2=CC(=O)CC[C@]12C | |
| External Links | ||
| DRUGBANK | DB00351 | |
| PubChem Compound | 11683 | |
| PDR | 1530 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.2 | - | 3.2 | - | DRUGBANK |
| Melting Point | 219.0 | ℃ | 218.0-220.0 | ℃ | DRUGBANK |
| Water Solubility | 2.0 | mg/L | 2 | μg/ml | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Metabolic | 6.5 | % | 5-8 | % | Urinary excretion; | DRUGBANK |
| Half-life | 34.0 | h | 34 | h | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adolescents | 800.0 | mg/day | 800 | mg/day | Liquid | Megestrol Acetate | megestrol acetate | PDR |
| Max dose for adolescents | 625.0 | mg/day | 625 | mg/day | Liquid | Megestrol Acetate | megestrol acetate | PDR |
| Max dose for adults | 800.0 | mg/day | 800 | mg/day | Liquid | Megestrol Acetate | megestrol acetate | PDR |
| Max dose for adults | 625.0 | mg/day | 625 | mg/day | Liquid | Megestrol Acetate | megestrol acetate | PDR |
| Max dose for elderly | 800.0 | mg/day | 800 | mg/day | Liquid | Megestrol Acetate | megestrol acetate | PDR |
| Max dose for elderly | 625.0 | mg/day | 625 | mg/day | Liquid | Megestrol Acetate | megestrol acetate | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1