Basic Information
| Drug ID | DDPD00342 |
|
| Drug Name | Terfenadine | |
| Molecular Weight | 471.6734 | |
| Molecular Formula | C32H41NO2 | |
| CAS Number | 50679-08-8 | |
| SMILES | CC(C)(C)C1=CC=C(C=C1)C(O)CCCN1CCC(CC1)C(O)(C1=CC=CC=C1)C1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB00342 | |
| T3DB | T3D2757 | |
| PubChem Compound | 5405 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 7.1 | - | 7.1 | - | DRUGBANK |
| Melting Point | 147.0 | ℃ | 147 | ℃ | PhysProp |
| Water Solubility | 0.0963 | mg/L | 0.0963 | mg/L | MCFARLAND,JW ET AL. 2001) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Absorption | 70.0 | % | >70 | % | PO, oral; | DRUGBANK |
| Half-life | 3.5 | h | 3.5 | h | DRUGBANK | |
| Toxicity LD50 | 5000.0 | mg/kg | 5.0 | g/kg | PO, oral; mouse; | DRUGBANK | Toxicity LD50 | 5000.0 | mg/kg | 5000.0 | mg/kg | PO, oral; mouse; | T3DB |
| Protein Binding | 70.0 | % | 70 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1