Basic Information
| Drug ID | DDPD00325 |
|
| Drug Name | Nitroprusside | |
| Molecular Weight | 215.938 | |
| Molecular Formula | C5FeN6O | |
| CAS Number | 15078-28-1 | |
| SMILES | O=N[Fe--](C#N)(C#N)(C#N)(C#N)C#N | |
| External Links | ||
| DRUGBANK | DB00325 | |
| T3DB | T3D0768 | |
| PubChem Compound | 11963622 | |
| PDR | 24055 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
Not Available
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 0.0333 | h | ~2 | min | DRUGBANK | |
| Toxicity LD50 | 2.8 | mg/kg | 2.8 | mg/kg | intravenous injection, IV; rabbit; | DRUGBANK | Toxicity LD50 | 5.0 | mg/kg | 5.0 | mg/kg | intravenous injection, IV; dog; | DRUGBANK | Toxicity LD50 | 8.4 | mg/kg | 8.4 | mg/kg | intravenous injection, IV; mouse; | DRUGBANK | Toxicity LD50 | 11.2 | mg/kg | 11.2 | mg/kg | intravenous injection, IV; Rattus, Rat; | DRUGBANK |
| Toxicity Lethal Dose | 250.0 | mg | 200-300 | mg | adults; human, homo sapiens; | T3DB |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for neonates | 14.4 | mg/kg/day | 10 | mcg/kg/minute | intravenous injection, IV | Nipride RTU | sodium nitroprusside | PDR |
| Max dose for infants | 14.4 | mg/kg/day | 10 | mcg/kg/min | intravenous injection, IV | Nipride RTU | sodium nitroprusside | PDR |
| Max dose for children | 14.4 | mg/kg/day | 10 | mcg/kg/minute | intravenous injection, IV | Nipride RTU | sodium nitroprusside | PDR |
| Max dose for adolescents | 14.4 | mg/kg/day | 10 | mcg/kg/minute | intravenous injection, IV | Nipride RTU | sodium nitroprusside | PDR |
| Max dose for adults | 14.4 | mg/kg/day | 10 | mcg/kg/min | intravenous injection, IV | Nipride RTU | sodium nitroprusside | PDR |
| Max dose for geriatric | 14.4 | mg/kg/day | 10 | mcg/kg/minute | intravenous injection, IV | Nipride RTU | sodium nitroprusside | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1