Basic Information
| Drug ID | DDPD00324 |
|
| Drug Name | Fluorometholone | |
| Molecular Weight | 376.4617 | |
| Molecular Formula | C22H29FO4 | |
| CAS Number | 426-13-1 | |
| SMILES | [H][C@@]12CC[C@](O)(C(C)=O)[C@@]1(C)C[C@H](O)[C@@]1(F)[C@@]2([H])C[C@H](C)C2=CC(=O)C=C[C@]12C | |
| External Links | ||
| DRUGBANK | DB00324 | |
| PubChem Compound | 9878 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.0 | - | 2.0 | - | HANSCH,C ET AL. (1995) |
| Melting Point | 297.5 | ℃ | 292-303 | ℃ | Fried, J.; U.S. Patent 2,852,51 September 16,1958; assigned to Olin Mathieson Chemical Corporation. ?Lincoln, F.H. Jr., Schneider, W.P. and Spero, G.B.; US. Patent 2,867,637; January 6, 1959; assigned to The Upjohn Company?. Lincoln, F.H. Jr., Schneider, W.P. and Spero, G.B.; U.S. Patent 2,867,638; January 6, 1959; assigned to The Upjohn Company. ?Magerlein, B.J., Kagan, F. and Schlagel, C.A.; U.S. Patent 3,038,914; June 12, 1962; assigned to The Upjohn Company. |
| Water Solubility | 30.0 | mg/L | 30 | mg/L | YALKOWSKY,SH & DANNENFELSER,RM 1992) |
| Log S | -4.1 | - | -4.1 | - | ADME Research, USCD |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Toxicity LD50 | 234.0 | mg/kg | 234.0 | mg/kg | Rattus, Rat; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1