Basic Information
| Drug ID | DDPD00322 |
|
| Drug Name | Floxuridine | |
| Molecular Weight | 246.1924 | |
| Molecular Formula | C9H11FN2O5 | |
| CAS Number | 50-91-9 | |
| SMILES | OC[C@H]1O[C@H](C[C@@H]1O)N1C=C(F)C(=O)NC1=O | |
| External Links | ||
| DRUGBANK | DB00322 | |
| PubChem Compound | 5790 | |
| PDR | 1378 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | -1.16 | - | -1.16 | - | HANSCH,C ET AL. (1995) |
| Melting Point | 150.5 | ℃ | 150.5 | ℃ | PhysProp |
| Water Solubility | 11900.0 | mg/L | 11900 | mg/L | DRUGBANK |
| pKa | 7.44 | - | 7.44 | - | SANGSTER (1994) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Toxicity LD50 | 215.0 | mg/kg | 215.0 | mg/kg | PO, oral; Rattus, Rat; | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 0.6 | mg/kg/day | 0.6 | mg/kg/day | intra-arterial infusion | Floxuridine | floxuridine | PDR |
| Max dose for elderly | 0.6 | mg/kg/day | 0.6 | mg/kg/day | intra-arterial infusion | Floxuridine | floxuridine | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1