Basic Information
| Drug ID | DDPD00309 |
|
| Drug Name | Vindesine | |
| Molecular Weight | 753.941 | |
| Molecular Formula | C43H55N5O7 | |
| CAS Number | 53643-48-4 | |
| SMILES | [H][C@@]12N3CC[C@@]11C4=CC(=C(OC)C=C4N(C)[C@@]1([H])[C@](O)([C@H](O)[C@]2(CC)C=CC3)C(N)=O)[C@]1(C[C@@]2([H])CN(C[C@](O)(CC)C2)CCC2=C1NC1=C2C=CC=C1)C(=O)OC | |
| External Links | ||
| DRUGBANK | DB00309 | |
| T3DB | T3D2479 | |
| PubChem Compound | 40839 | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 2.9 | - | 2.9 | - | DRUGBANK |
| Melting Point | 231.0 | ℃ | 230-232 | ℃ | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.13 | L/h/kg | 2.2 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 5.0 | L/kg | 5 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 24.0 | h | 24 | h | DRUGBANK | Half-life | 35.0 | h | 35 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Toxicity LD50 | 4.0 | mg/kg | 4.0 | mg/kg | mouse; | T3DB |
| Protein Binding | 70.0 | % | 65-75 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1