Property Name |
Property Value |
Unit |
Raw Value |
Raw Unit |
Annotation |
Reference |
Clearance |
1.7 |
L/h/kg |
29.0 |
ml/min/kg |
|
DRUGBANK |
Clearance |
1.6 |
L/h/kg |
26 |
ml/min/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Volume of Distribution |
11.0 |
L/kg |
11.0 |
L/kg |
|
DRUGBANK |
Volume of Distribution |
12.0 |
L/kg |
12 |
L/kg |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Half-life |
6.0 |
h |
6(2-12) |
h |
|
DRUGBANK |
Half-life |
7.0 |
h |
7 |
h |
intravenous injection, IV; human, homo sapiens; |
Human Intravenous Pharmacokinetic Dataset |
Toxicity LD50 |
50.0 |
mg/kg |
>50 |
mg/kg |
intravenous injection, IV; Rattus, Rat; |
DRUGBANK |
Eliminate Route |
82.0 |
% |
~82 |
% |
Urinary excretion; Male, men; normal,healthy; human, homo sapiens; |
DRUGBANK |
Eliminate Route |
19.0 |
% |
~19 |
% |
Faeces excretion; Male, men; normal,healthy; human, homo sapiens; |
DRUGBANK |
Eliminate Route |
7.0 |
% |
~7 |
% |
Urinary excretion; Male, men; normal,healthy; human, homo sapiens; Unchanged drug; |
DRUGBANK |
Protein Binding |
40.0 |
% |
40 |
% |
|
DRUGBANK |