Basic Information
| Drug ID | DDPD00307 |
|
| Drug Name | Bexarotene | |
| Molecular Weight | 348.4779 | |
| Molecular Formula | C24H28O2 | |
| CAS Number | 153559-49-0 | |
| SMILES | CC1=CC2=C(C=C1C(=C)C1=CC=C(C=C1)C(O)=O)C(C)(C)CCC2(C)C | |
| External Links | ||
| DRUGBANK | DB00307 | |
| PubChem Compound | 82146 | |
| PDR | 145 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 6.9 | - | 6.9 | - | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Half-life | 7.0 | h | 7 | h | DRUGBANK | |
| Eliminate Route | 1.0 | % | <1 | % | Urinary excretion; | DRUGBANK |
| Protein Binding | 99.0 | % | >99 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for adults | 400.0 | mg/m2/day | 400 | mg/m2/day | PO, oral | Targretin Capsules | bexarotene | PDR |
| Max dose for adults | 1.0 | appLication | 1 | appLication | gel | Targretin Capsules | bexarotene | PDR |
| Max dose for geriatric | 400.0 | mg/m2/day | 400 | mg/m2/day | Capsule, PO, Oral | Targretin Capsules | bexarotene | PDR |
| Max dose for geriatric | 1.0 | application | 1 | application | gel | Targretin Capsules | bexarotene | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1