Basic Information

Drug ID DDPD00293 ...
Drug Name Raltitrexed
Molecular Weight 458.488
Molecular Formula C21H22N4O6S
CAS Number 112887-68-0
SMILES CN(CC1=CC2=C(NC(C)=NC2=O)C=C1)C1=CC=C(S1)C(=O)N[C@@H](CCC(O)=O)C(O)=O
External Links
DRUGBANK DB00293
PubChem Compound 104758

Experimental Physicochemical Property

Property Name Property Value Unit Raw Value Raw Unit Reference
Log P -1.2 - -1.2 - DRUGBANK
Melting Point 182.0 180-184 DRUGBANK

Pharmacokinetic/ Toxicokinetic Property

Property Name Property Value Unit Raw Value Raw Unit Annotation Reference
Clearance 0.0540 L/h/kg 0.9 ml/min/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Volume of Distribution 6.6 L/kg 6.57 L/kg intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Half-life 198.0 h 198 h DRUGBANK
Half-life 140.0 h 140 h intravenous injection, IV; human, homo sapiens; Human Intravenous Pharmacokinetic Dataset
Protein Binding 93.0 % >93 % DRUGBANK

Maximum Dosage

Not Available

Drug Property Radar Chart

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Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1