Basic Information
| Drug ID | DDPD00292 |
|
| Drug Name | Etomidate | |
| Molecular Weight | 244.289 | |
| Molecular Formula | C14H16N2O2 | |
| CAS Number | 33125-97-2 | |
| SMILES | CCOC(=O)C1=CN=CN1[C@H](C)C1=CC=CC=C1 | |
| External Links | ||
| DRUGBANK | DB00292 | |
| PubChem Compound | 667484 | |
| PDR | 675 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 3.05 | - | 3.05 | - | POMONA (1987) |
| Melting Point | 142.4 | ℃ | 142-142.8 | ℃ | Godefroi, E.F. and Van Der Eijcken, C.A.M.; U.S. Patent 3,354,173; November 21, 1967; assigned to Janssen Pharrnaceutica NV (Belgium). |
| Water Solubility | 63.2 | mg/L | 63.2 | mg/L | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.78 | L/h/kg | 13 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 2.7 | L/kg | 2.7 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 1.3 | h | 75 | min | DRUGBANK | Half-life | 3.5 | h | 3.5 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Eliminate Route | 75.0 | % | ~75 | % | Urinary excretion; | DRUGBANK |
| Protein Binding | 76.0 | % | 76 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1