Basic Information
| Drug ID | DDPD00291 |
|
| Drug Name | Chlorambucil | |
| Molecular Weight | 304.212 | |
| Molecular Formula | C14H19Cl2NO2 | |
| CAS Number | 305-03-3 | |
| SMILES | OC(=O)CCCC1=CC=C(C=C1)N(CCCl)CCCl | |
| External Links | ||
| DRUGBANK | DB00291 | |
| T3DB | T3D4684 | |
| PubChem Compound | 2708 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 1.7 | - | 1.7 | - | HANSCH,C ET AL. (1995), pH 7.4 |
| Melting Point | 65.0 | ℃ | 65 | ℃ | PhysProp |
| Water Solubility | 12400.0 | mg/L | 12400 | mg/L | DRUGBANK |
| pKa | 5.75 | - | 5.75 | - | HANSCH,C & LEO,AJ (1987) |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Clearance | 0.17 | L/h/kg | 2.8 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.26 | L/kg | 0.26 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 1.5 | h | 1.5 | h | DRUGBANK | Half-life | 1.1 | h | 1.1 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Protein Binding | 99.0 | % | 99 | % | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1