Basic Information
| Drug ID | DDPD00290 |
|
| Drug Name | Bleomycin | |
| Molecular Weight | 1415.552 | |
| Molecular Formula | C55H84N17O21S3 | |
| CAS Number | 11056-06-7 | |
| SMILES | [H][C@](C)(NC(=O)[C@@]([H])(NC(=O)C1=NC(=NC(N)=C1C)[C@H](CC(N)=O)NC[C@H](N)C(N)=O)[C@@]([H])(OC1OC(CO)C(O)C(O)C1OC1OC(CO)C(O)C(OC(N)=O)C1O)C1=CNC=N1)[C@@H](O)[C@H](C)C(=O)N[C@]([H])(C(=O)NCCC1=NC(=CS1)C1=NC(=CS1)C(=O)NCCC[S+](C)C)[C@@]([H])(C)O | |
| External Links | ||
| DRUGBANK | DB00290 | |
| T3DB | T3D2738 | |
| PubChem Compound | 5360373 | |
| PDR | 1444 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Melting Point | 71.0 | ℃ | 71 | ℃ | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| Bioavailability | 45.0 | % | 45.0 | % | DRUGBANK | |
| Clearance | 0.0756 | L/h/kg | 1.26 | ml/min/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Volume of Distribution | 0.43 | L/kg | 0.43 | L/kg | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Half-life | 1.9 | h | 115 | min | DRUGBANK | Half-life | 3.9 | h | 3.9 | h | intravenous injection, IV; human, homo sapiens; | Human Intravenous Pharmacokinetic Dataset |
| Protein Binding | 1.0 | % | 1 | % | DRUGBANK |
Maximum Dosage
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Brand Name | Component | Reference |
|---|---|---|---|---|---|---|---|---|
| Max dose for children | 400.0 | units | 400 | units | intravenous injection, IV;IM,intramuscular injection;subcutaneous injection, SC; | Bleomycin | bleomycin sulfate | PDR |
| Max dose for adolescents | 400.0 | units | 400 | units | intravenous injection, IV;IM,intramuscular injection;subcutaneous injection, SC; | Bleomycin | bleomycin sulfate | PDR |
| Max dose for geriatric | 400.0 | units | 400 | units | intravenous injection, IV;IM,intramuscular injection;subcutaneous injection, SC; | Bleomycin | bleomycin sulfate | PDR |
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1