Basic Information
| Drug ID | DDPD00287 |
|
| Drug Name | Travoprost | |
| Molecular Weight | 500.5477 | |
| Molecular Formula | C26H35F3O6 | |
| CAS Number | 157283-68-6 | |
| SMILES | CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COC1=CC=CC(=C1)C(F)(F)F | |
| External Links | ||
| DRUGBANK | DB00287 | |
| PubChem Compound | 5282226 | |
| Drugs.com | Drugs.com Drug Page | |
Experimental Physicochemical Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Reference |
|---|---|---|---|---|---|
| Log P | 4.6 | - | 4.6 | - | DRUGBANK |
| Water Solubility | 16000.0 | mg/L | >16 | mg/ml | DRUGBANK |
Pharmacokinetic/ Toxicokinetic Property
| Property Name | Property Value | Unit | Raw Value | Raw Unit | Annotation | Reference |
|---|---|---|---|---|---|---|
| C Max | 0.0250 | ng/ml | <25 | pg/ml | ophthalmic administration; | DRUGBANK |
| T Max | 0.50 | h | 0.5 | h | ophthalmic administration; | DRUGBANK |
| Volume of Distribution | 2.6 | L/kg | 2.6 | L/kg | Rattus, Rat; | DRUGBANK |
| Half-life | 0.75 | h | ~45(17-86) | min | elimination half-life; | DRUGBANK |
| Eliminate Route | 61.0 | % | 61 | % | Bile excretion; subcutaneous injection, SC; Rattus, Rat; | DRUGBANK | Eliminate Route | 34.0 | % | 34 | % | Urinary excretion; subcutaneous injection, SC; Rattus, Rat; | DRUGBANK |
| Protein Binding | 80.0 | % | 80 | % | plasma proteins; | DRUGBANK |
Maximum Dosage
Not Available
Drug Property Radar Chart
Note: Center: Q1-1.5*IQR, Edge: Q3+1.5*IQR; Q1: Quantile 1, Q3: Quantile 3, IQR: Q3-Q1